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Natural-Language-Guided Generator-Agnostic Shortlisting for Protein Binder Desig

BACKGROUND
2 SIGNALSFIRST DETECTED 24 August 2026
Narrative synthesis pending — 2 signals collected.
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8 May
ProtDBench: A Unified Benchmark of Protein Binder Design and Evaluation

arXiv:2605.04118v1 Announce Type: cross Abstract: Recent advances in de novo protein binder design have enabled increasing experimental validation, yet reported in silico metrics

REPORT · WHAT · ArXiv CS.AIOPEN STORY
27 Apr
MolClaw: An Autonomous Agent with Hierarchical Skills for Drug Molecule Evaluation, Screening, and Optimization

arXiv:2604.21937v1 Announce Type: new Abstract: Computational drug discovery, particularly the complex workflows of drug molecule screening and optimization, requires

REPORT · WHAT · ArXiv CS.AIOPEN STORY
7 Sept
ProtLingo: Efficient Protein Language Modeling via Conditional Memory and Expert Routing

arXiv:2609.04793v1 Announce Type: new Abstract: Proteins perform diverse cellular functions, and even single amino-acid substitutions can alter stability, activity, or molecular

REPORT · HOW · ArXiv CS.AIOPEN STORY
4 May
Minimal, Local, Causal Explanations for Jailbreak Success in Large Language Models

arXiv:2605.00123v1 Announce Type: new Abstract: Safety trained large language models (LLMs) can often be induced to answer harmful requests through jailbreak prompts. Because we

REPORT · WHAT · ArXiv CS.AIOPEN STORY
30 Jun
Two-Stage Fine-Tuning for Protein Sequence Generation with Targeted Amino-Acid Composition

arXiv:2606.27939v1 Announce Type: cross Abstract: Protein language models are standard priors for biological sequence generation, but steering them toward explicit distributional

REPORT · WHAT · ArXiv CS.AIOPEN STORY
2 Oct
Measuring the Microtask Eligibility Gap: When Is an Off-the-Shelf SLM Enough for an Agent Harness?

arXiv:2610.00025v1 Announce Type: new Abstract: Agent harnesses increasingly want to run small language models (SLMs) on the microtasks around a frontier large language model

REPORT · WHEN · ArXiv CS.AIOPEN STORY
11 May
CASCADE: Case-Based Continual Adaptation for Large Language Models During Deployment

arXiv:2605.06702v1 Announce Type: new Abstract: Large language models (LLMs) have become a central foundation of modern artificial intelligence, yet their lifecycle remains

REPORT · WHAT · ArXiv CS.AIOPEN STORY
16 Apr
Numerical Instability and Chaos: Quantifying the Unpredictability of Large Language Models

arXiv:2604.13206v1 Announce Type: new Abstract: As Large Language Models (LLMs) are increasingly integrated into agentic workflows, their unpredictability stemming from numerical

REPORT · WHAT · ArXiv CS.AIOPEN STORY
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